Neblio focuses on simplicity for developers, users and clients. The basis of Neblio's approach is its RestFull API interfaces, which act as an interpreter for programs and applications that interact with the Neblio blockchain. The APIs connect clients and processes with their distributed peer-to-peer nodes. Neblio offers APIs in programming languages such as Java, Ruby, Go, PHP, Python, javascript, C# and Objective-C.

Applications can be programmed in any of the supported API languages, which can request or publish data on the Neblio blockchain using these APIs. The API interfaces allow developers and clients to program in the languages that are most convenient for them, instead of forcing users to develop applications in a language specific to blockchains, for example, Ethereum Solidity or Zilliqa Silica.

One of the advantages of programming using the Neblio API is the modular nature of this platform. Support for a multilingual API in Neblio adds design flexibility and expands the pool of experienced developers who can easily create and deploy applications on the Neblio blockchain.

The Neblio blockchain itself is a PoS chain based on the Peercoin mechanism with minor modifications. Neblio does not require a minimum amount of NEBL to ensure network security. The coin maturity, or the amount of time a group of coins must be stored in a wallet before they can stake, was changed to 24 hours, and the stake payout was increased to 10% annual rewards. In addition, the block time was normalized to 120 seconds. The Neblio hashing algorithm is Scrypt, which is most widely used in Litecoin.

The pre-sale, or ICO of Neblio, began on August 6, 2017. Unlike many ICOs over the past two years, the Neblio team had already implemented a working network and developed three Neblio Core desktop wallets for Windows, MacOS and Linux. Uniquely, all tokens were put up for the ICO, and even the Neblio developers had to buy Neblio tokens in their own ICO. Upon purchase, the tokens were immediately distributed to the ICO participants. Initially 125 million NEBL were put up for sale during the ICO, but the team did not sell all the tokens; in fact only 11.75 million tokens were sold. After the ICO, the vast majority of the tokens intended for sale in the ICO were burned, as a result of which the total supply of tokens decreased to just over 12 million NEBL.